The simplest Methamphetamine synthesis from Amphetamine

[BongMan]

i don't know what gone wrong but i lost almost 20 gm of pure amphetamine , i tried to neutralist it with NaOH, and extract with petroleum ether nothing was left on evaporation , tried again with DCM again nothing left on evaporation , guys anybody tried this method , if anyone going to try use small quantity ..

 

[redsm]

i don't know what gone wrong but i lost almost 20 gm of pure amphetamine , i tried to neutralist it with NaOH, and extract with petroleum ether nothing was left on evaporation , tried again with DCM again nothing left on evaporation , guys anybody tried this method , if anyone going to try use small quantity ..

BongManare you referring to the first step of the synthesis?

if you are failing with conversion of amphetamine salt to freebase you need to learn basic chemistry skills. try an organic chemistry textbook as well as a practical/experimental organic chemistry guidebook.

 

[metux]

i don't know what gone wrong but i lost almost 20 gm of pure amphetamine , i tried to neutralist it with NaOH, and extract with petroleum ether nothing was left on evaporation , tried again with DCM again nothing left on evaporation , guys anybody tried this method , if anyone going to try use small quantity ..

BongMan20gram is alot,i think you need more practise,but doint lose another 20gram mate,you can start 1gram scale

 

[BongMan]

20gram is alot,i think you need more practise,but doint lose another 20gram mate,you can start 1gram scale

metuxi tried with it 4-5 times so i lost total 20 gm.

 

[cokemuffin]

i tried with it 4-5 times so i lost total 20 gm.

BongManMaybe your stuff is shit?

 

[zxkcasldlalsejak]

1. 1 L Of cooled distilled water is added to the reaction mass, aluminum hydroxide solids are filtered off.
2. The whole reaction mass is treated with 20 % HCl to pH 3 and extracted by DCM or petrolium ether 3 x 75 mL. DCM extracts are combined. Resulting water layer from filtration is alkalinized by 20% NaOH aq to pH 12 and extracted with DCM or petrolium ether 3 x 75 mL. Organic layers with methamphetamine (4) are combined (from first and second extraction of alkilized water layer), dried over Na2SO4 or MgSO4 anhydrous and concentrated in vacuum.

Sorry but for me is still absolutely not clear...

We've got some gray cream with a little bit of aluminium hydroxide solids. I believe that we have in this mass mix of crude freebase meth which is organic layer and a little bit of water layer (maybe they wont be easy to separate). Then we add a lot of water (maybe for decrease density of our mass).
But still - as i understand we have organic layer up and water layer at the bottom.
When we filtrate it from some solids , we still have two layers - organic up and water at the bottom. The organic layer shoud contain our product.
Then we acidify this mass with hcl to ph3 which change the crude meth contained in organic layer into meth hcl which should go to water layer.
But still we have two layers. what exactly we are already extracting by dcm.
Dcm will go to the bottom below water layer but when the ph is 3 the water layer still wont give back the meth hcl.
So now we have 3 layers. Up organic with hell know what inside, second water layer with meth hcl and bottom dcm layer with what?

 

[Ra226]

I have a few questions that need to be answered, and in return I will publish for free some important data on amphetamines and their precursors that this website lacks after the next test is completed.
1.Can D-amphetamine hydrochloride crystals be sold and smoked as Ice? (Ice refers to D-methamphetamine hydrochloride crystals.If there is not much difference in function between them, I plan to directly declare that D-amphetamine hydrochloride crystals are D-methamphetamine hydrochloride crystals.)
2.Are the smoke concentrations/odors of D-amphetamine hydrochloride crystals and D-methamphetamine hydrochloride crystals burning and atomizing consistent?
3.For some reason I can't smoke meth on my own, but can anyone tell me what exactly meth is supposed to smell like? I've smelled pure amphetamine hydrochloride powder and it smells like a bayberry or cranberry scent combined with a grassy plant sap scent. When heated and atomized, it smells a bit strange, but its afternote makes me feel like I understand why ICE is called "pork". Is this smell correct?
4.I know that D-amphetamine is less effective than D-methamphetamine at the same dose, but how much weaker is it than D-methamphetamine? For example, is it equivalent to 75% or 70% of D-methamphetamine at the same dose?Will there be a significant difference in personal subjective experience in the case of heated atomization inhalation?
5.Considering that the ICE sold on the market is not actually pure D-methamphetamine, dealers mix in some "excipients" to increase weight and increase profits. This results in the effect of commercially available ICE being inferior to pure D-methamphetamine at the same dose.so I think this should be enough to offset the potency gap between D-methamphetamine and D-amphetamine. Even if I claim that D-amphetamine is ICE, it will not cause after-sales problems. Is this idea feasible?

 

[cokemuffin]

I have a few questions that need to be answered, and in return I will publish for free some important data on amphetamines and their precursors that this website lacks after the next test is completed.
1.Can D-amphetamine hydrochloride crystals be sold and smoked as Ice? (Ice refers to D-methamphetamine hydrochloride crystals.If there is not much difference in function between them, I plan to directly declare that D-amphetamine hydrochloride crystals are D-methamphetamine hydrochloride crystals.)
2.Are the smoke concentrations/odors of D-amphetamine hydrochloride crystals and D-methamphetamine hydrochloride crystals burning and atomizing consistent?
3.For some reason I can't smoke meth on my own, but can anyone tell me what exactly meth is supposed to smell like? I've smelled pure amphetamine hydrochloride powder and it smells like a bayberry or cranberry scent combined with a grassy plant sap scent. When heated and atomized, it smells a bit strange, but its afternote makes me feel like I understand why ICE is called "pork". Is this smell correct?
4.I know that D-amphetamine is less effective than D-methamphetamine at the same dose, but how much weaker is it than D-methamphetamine? For example, is it equivalent to 75% or 70% of D-methamphetamine at the same dose?Will there be a significant difference in personal subjective experience in the case of heated atomization inhalation?
5.Considering that the ICE sold on the market is not actually pure D-methamphetamine, dealers mix in some "excipients" to increase weight and increase profits. This results in the effect of commercially available ICE being inferior to pure D-methamphetamine at the same dose.so I think this should be enough to offset the potency gap between D-methamphetamine and D-amphetamine. Even if I claim that D-amphetamine is ICE, it will not cause after-sales problems. Is this idea feasible?

Ra226Tbh D-amphetamine HCl ain't worth the struggle and smoking amphetamine ain't worth it either. The myth that you can smoke amphetamine HCl is in my opinion just a myth, i've never seen any reliable evidence that you can actually smoke amphetamine HCl. Even if you'd manage to somehow smoke it you won't get a rush from smoking amphetamine like you get from methamphetamine due to the decreased lipid solubility of amphetamine (higher lipid solubility equals faster onset of action due to faster crossing the blood-brain barrier). Besides that the HCl salt is higly hygroscopic and probably doesn't look like ICE even if you'd sepereate the enantiomers. When it comes to Potency it ain't that simple, D-methamphetamine isn't just more potent D-amphetamine, regarding to some dosage charts D-amphetamine is even more potent than D-methamphetamine on a mg to mg comparison. The issue is D-amphetamine lacks serotonergic effects and therefore will feel different to a regular ICE user than usual D-methamphetamine, so to cut it off it you'll get a shit ton of sales problems and would be better setup if you'd either make Meth or Speed and sell it as what it is.

 

[Melv99]

“as Grandma Blows out a cloud of Amp Hcl”

Say what? Just regurgitating nonsense again?

 

[9-Tryptophan]

I tried the synthesis with 10g and everything looked very good, I even think I smelled methamphetamine while I filtrated the RM.

Stupidly, I forgot to concentrate and dry the extractions in the last step and bubbled HCl straight in.
The petroleum ether became cloudy at first and when I continued, a yellow liquid collected at the bottom, but only a small amount (1-2ml)

Now I have it the concentrate of petroleum ether, methamphetamine and HCl Gas. Has anyone a idea how to save it at this point?

 

[wael gano]

I tried the synthesis with 10g and everything looked very good, I even think I smelled methamphetamine while I filtrated the RM.

Stupidly, I forgot to concentrate and dry the extractions in the last step and bubbled HCl straight in.
The petroleum ether became cloudy at first and when I continued, a yellow liquid collected at the bottom, but only a small amount (1-2ml)

Now I have it the concentrate of petroleum ether, methamphetamine and HCl Gas. Has anyone a idea how to save it at this point?

9-TryptophanDo you have a free base in the ether?
Or salt?
Please multiply the hydrogen chloride gas while reducing the volume of ether

 

[9-Tryptophan]

Do you have a free base in the ether?
Or salt?
Please multiply the hydrogen chloride gas while reducing the volume of ether

wael ganoI had the freebase dissolved in the ether and bubbled HCl Gas into it without reducing the volume. So i guess it's now the HCl salt somehow dissolved in the ether but I don't really know.

I try now to reduce the volume but slowly under cooling because I fear that the HCl produced in the ether will hydrolyze the methamphetamin.

 

[wael gano]

I had the freebase dissolved in the ether and bubbled HCl Gas into it without reducing the volume. So i guess it's now the HCl salt somehow dissolved in the ether but I don't really know.

I try now to reduce the volume but slowly under cooling because I fear that the HCl produced in the ether will hydrolyze the methamphetamin.

9-TryptophanDid you use hydrochloric acid water

 

[9-Tryptophan]

Did you use hydrochloric acid water

wael ganoNo I generated HCl from NaCl and H2SO4 but I didn't dried it and bubbled it straight to the ether extract. A little bit of HCl definitely dissolved into the ether because it releases HCl Vapour.

 

[wael gano]

No I generated HCl from NaCl and H2SO4 but I didn't dried it and bubbled it straight to the ether extract. A little bit of HCl definitely dissolved into the ether because it releases HCl Vapour.

9-TryptophanYou must reduce or eliminate the volume of ether, add ethanol to the base, and blow on the steam

 

[wael gano]

No I generated HCl from NaCl and H2SO4 but I didn't dried it and bubbled it straight to the ether extract. A little bit of HCl definitely dissolved into the ether because it releases HCl Vapour.

9-TryptophanAre you sure you extracted the meth base?

 

[9-Tryptophan]

Are you sure you extracted the meth base?

wael ganoI think I extracted it, at least I did everything right.

After filtering out the amalgam and hydroxide, I added a few HCl acid to rm until it was pH 3 and extracted it with ether 3 times.
Then I alkalized it with NaOH to PH 12 and extracted again 3 times.

How do you mean? After reducing the volume "add ethanol to the base, and blow on the steam"

 

[wael gano]

I think I extracted it, at least I did everything right.

After filtering out the amalgam and hydroxide, I added a few HCl acid to rm until it was pH 3 and extracted it with ether 3 times.
Then I alkalized it with NaOH to PH 12 and extracted again 3 times.

How do you mean? After reducing the volume "add ethanol to the base, and blow on the steam"

9-TryptophanI added hydrochloric acid and extracted with ether
then. Add alkali and extract again
Then collect the extracts and evaporate the ether and keep the free base. Add some ethanol to it and create hydrogen chloride vapor for the free base in the ethanol.

 

[9-Tryptophan]

I think I extracted it, at least I did everything right.

After filtering out the amalgam and hydroxide, I added a few HCl acid to rm until it was pH 3 and extracted it with ether 3 times.
Then I alkalized it with NaOH to PH 12 and extracted again 3 times.

How do you mean? After reducing the volume "add ethanol to the base, and blow on the steam"

 

[DrGodMan]

Result with 1g / 1 mole Amphetamine salt ?